RELAXIN RECEPTOR 1 FOR USE IN TREATMENT AND PREVENTION OF HEART FAILURE

The present invention relates to a polynucleotide comprising an expressible nucleic acid sequence encoding a relaxin family peptide receptor (RXFP) polypeptide for use in treatment and/or prevention of heart failure in a subject. The present invention further relates to a vector comprising the polyn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAAKE, Philip Wolfram Joseph, SCHLEGEL, Philipp, KATUS, Hugo, SASIPONG, Nuttarak
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a polynucleotide comprising an expressible nucleic acid sequence encoding a relaxin family peptide receptor (RXFP) polypeptide for use in treatment and/or prevention of heart failure in a subject. The present invention further relates to a vector comprising the polynucleotide of the present invention for use in treatment and/or prevention of heart failure, as well as to host cells, RXFP agonists, kits and devices related thereto.