XYLR Mutant For Improved Xylose Utilization Or Improved Co-Utilization Of Glucose And Xylose

The disclosure relates to mutant gene(s) that confer upon microorganisms that express them an improved capacity to utilize xylose and improved capacity to co-utilize glucose and xylose thereby resulting in improved growth of the microorganism. Further encompassed are methods of producing fatty acids...

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Bibliographische Detailangaben
Hauptverfasser: FRYKMAN, Scott Allen, DA COSTA, Bernardo Moura Torres, PAYNE, Stephen Thomas, CALLIHAN, Isolde, WONG, Leland Ken, VENKITESWARAN, Sankaranarayanan
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure relates to mutant gene(s) that confer upon microorganisms that express them an improved capacity to utilize xylose and improved capacity to co-utilize glucose and xylose thereby resulting in improved growth of the microorganism. Further encompassed are methods of producing fatty acids and fatty acid derivatives from cellulosic biomass, xylose, and/or a glucose/xylose mix by employing the host cells expressing the engineered XylR variants and compositions of biologically produced fatty acids and fatty acid derivatives.