PREVENTION OF LOCAL TUMOR RECURRENCE FOLLOWING SURGERY USING SUSTAINEDAND/OR DELAYED RELEASE OF MEDICAMENTS CONTAINED IN MICRO-PARTICLES

PREVENTION OF LOCAL TUMOR RECURRENCE FOLLOWING SURGERY USING SUSTAINEDAND/OR DELAYED RELEASE OF MEDICAMENTS CONTAINED IN MICRO-PARTICLES

Provided herein are methods and compositions for treatment of a patient having a wound resulting from surgical resection of a tumor mass. In some embodiments, the methods provided herein include administering to the entirety of the wound area a composition before the wound area is closed, the compos...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hahn, Soon Kap, Kim, Gil Man, Seo, Min Hyo, Gotov, Oyuntuya, Battogtokh, Gantumur
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided herein are methods and compositions for treatment of a patient having a wound resulting from surgical resection of a tumor mass. In some embodiments, the methods provided herein include administering to the entirety of the wound area a composition before the wound area is closed, the composition having a first plurality of micro-particles comprising PLGA and one or more cancer treatment drugs, and a second plurality of micro-particles comprising PLGA and one or more wound healing drugs; wherein the wound healing drugs are released for a first period of time and the cancer treatment drugs are released for a second period of time without an initial burst release.