USE OF MONENSIN TO REGULATE GLYCOSYLATION OF RECOMBINANT PROTEINS

Methods of modulating the properties of a cell culture expressing a protein of interest are provided. In various embodiments the methods relate to the addition of cell-cycle inhibitors to growing cell cultures.

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Bibliographische Detailangaben
Hauptverfasser: PANDE, Sandhya, MUJACIC, Mirna
Format: Patent
Sprache:eng
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Zusammenfassung:Methods of modulating the properties of a cell culture expressing a protein of interest are provided. In various embodiments the methods relate to the addition of cell-cycle inhibitors to growing cell cultures.