BALLOON CATHETER SYSTEM FOR INFUSION OF MICELLES AT HIGH PRESSURE

A balloon catheter system for infusion of micelles at high pressure. The system includes a catheter with a drug eluting balloon with a perforated wall with numerous pores, a reservoir of nanoparticles in an aqueous solution disposed within the balloon or in fluid communication with the balloon. The...

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Bibliographische Detailangaben
Hauptverfasser: BAUMBACH, William R, SHERMAN, Darren R
Format: Patent
Sprache:eng
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Zusammenfassung:A balloon catheter system for infusion of micelles at high pressure. The system includes a catheter with a drug eluting balloon with a perforated wall with numerous pores, a reservoir of nanoparticles in an aqueous solution disposed within the balloon or in fluid communication with the balloon. The particles may comprise drug loaded micelles, where the micelles are provided in the size range of 40 to 250 nm generally (0.040 μm to 0.250 μm), and the pores of the balloon wall are configured to allow passage of the micelles with a minimum of disruption, The pores are conical, with the diameter of the pore at the inside of the balloon wall smaller than the diameter of the pores at the outside of the balloon wall.