SYNTHETIC HEME-CONTAINING MOLECULES AND THEIR USE

SYNTHETIC HEME-CONTAINING MOLECULES AND THEIR USE

Synthetic heme-containing molecules are described. The heme-containing molecules include a heme group bound to either two non-contiguous peptides or a single contiguous peptide via cysteine residues. Use of the synthetic heme-containing molecules, such as for the treatment of carboxyhemoglobinemia,...

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Bibliographische Detailangaben
Hauptverfasser: DeMartino, Anthony W, Tejero Bravo, Jesus, Islam, Kazi R, Yurko, Raymond B, Rose, Jason J, Gladwin, Mark T
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Synthetic heme-containing molecules are described. The heme-containing molecules include a heme group bound to either two non-contiguous peptides or a single contiguous peptide via cysteine residues. Use of the synthetic heme-containing molecules, such as for the treatment of carboxyhemoglobinemia, cyanide poisoning and hydrogen sulfide (H2S) poisoning, is further described.