METHODS OF ISOLATING AND USING DESCEMET'S MEMBRANE AND COMPOSITIONS INCLUDING ISOLATED DESCEMET'S MEMBRANE

This disclosure describes methods of preparing a decellularized Descemet's membrane and an isolated Descemet's membrane, methods of using an isolated Descemet's membrane, and tissues prepared using an isolated Descemet's membrane. This disclosure further describes a composition t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hou, Joshua Honghan, Bedard, Peter, Yuan, Ching
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This disclosure describes methods of preparing a decellularized Descemet's membrane and an isolated Descemet's membrane, methods of using an isolated Descemet's membrane, and tissues prepared using an isolated Descemet's membrane. This disclosure further describes a composition that includes an isolated Descemet's membrane. In some embodiments, the tissues and methods described herein may be used to treat a limbal stem cell deficiency or as an ocular surface bandage.