Cyclic compounds as receptor modulating therapeutics and methods and uses thereof

The present invention relates generally to chemical compounds of formula (I) and methods for their use and preparation. In particular, the invention relates to chemical compounds which are useful in relation to the treatment of diseases, disorders or conditions which would benefit from the modulatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huff, Belinda, Toop, Hamish, Contreras, Jean-Marie, Morice, Christophe, Schaeffer, Laurent, Mitchell, Lorna, Singh, Rajinder, Bazzini, Patrick, Michaut, Mathieu, Ripper, Justin
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates generally to chemical compounds of formula (I) and methods for their use and preparation. In particular, the invention relates to chemical compounds which are useful in relation to the treatment of diseases, disorders or conditions which would benefit from the modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR), such as anxiety, depression and stress related disorders.