NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

NONAPEPTIDE PREVENTING INCREASED HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.

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Bibliographische Detailangaben
Hauptverfasser: SAMSONOV, Mikhail Vasilievich, MOLOKOEDOV, Aleksandr Sergeevich, KAZAKOVA, Olga Alekseevna, KHAPCHAEV, Asker Yusufovich, AZMUKO, Andrey Andreevich, OVCHINNIKOV, Mihail Vladimirovich, SHIRINSKY, Vladimir Pavlovich, ARZAMASCEV, Yevgeniy Veniaminovich, BUSHUEV, Valeri Nikolaevich, TEREKHOVA, Olga Alexandrovna, PALKEEVA, Marina Yevgenievna, SIDOROVA, Mariya Vladimirovna
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The invention relates to a low-toxicity, proteolysis-resistant biologically active nonapeptide of formula (I) that is capable of preventing vascular hyperpermeability in stressful situations. Owing to said property, the claimed peptide can be used in medicine as an anti-edematous agent.