COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND PLATINUM-BASED ANTICANCER AGENT

A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocycli...

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Hauptverfasser: ZEPEDA OROZCO, Diana, DAVIS, Andrew Blake, KEENE, Jeffery L, RILEY, Dennis P, BEARDSLEY, Robert A, STORY, MICHAEL DEAN, SPITZ, Jr., Douglas R, ALLEN, Bryan G, MAPUSKAR, Kranti Ashok
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creator ZEPEDA OROZCO, Diana
DAVIS, Andrew Blake
KEENE, Jeffery L
RILEY, Dennis P
BEARDSLEY, Robert A
STORY, MICHAEL DEAN
SPITZ, Jr., Douglas R
ALLEN, Bryan G
MAPUSKAR, Kranti Ashok
description A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocyclic ring complex corresponding to the Formula (I) below, prior to, concomitantly with, or after administration of the platinum-based anticancer agent, whereby response of the cancer to the platinum-based anticancer agent is increased.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND PLATINUM-BASED ANTICANCER AGENT
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