COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND PLATINUM-BASED ANTICANCER AGENT

COMBINATION CANCER THERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX AND PLATINUM-BASED ANTICANCER AGENT

A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocycli...

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Bibliographische Detailangaben
Hauptverfasser: ZEPEDA OROZCO, Diana, DAVIS, Andrew Blake, KEENE, Jeffery L, RILEY, Dennis P, BEARDSLEY, Robert A, STORY, MICHAEL DEAN, SPITZ, Jr., Douglas R, ALLEN, Bryan G, MAPUSKAR, Kranti Ashok
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocyclic ring complex corresponding to the Formula (I) below, prior to, concomitantly with, or after administration of the platinum-based anticancer agent, whereby response of the cancer to the platinum-based anticancer agent is increased.