REPORTER NUCLEIC ACIDS FOR TYPE V CRISPR-MEDIATED DETECTION

The present disclosure provides labeled single stranded detector DNA molecules that provide a sensitive readout for detection of a target DNA. The present disclosure provides compositions, systems, and kits comprising a labeled single stranded detector DNA of the present disclosure. The present disc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Janice S, Doudna, Jennifer A, Harrington, Lucas Benjamin
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides labeled single stranded detector DNA molecules that provide a sensitive readout for detection of a target DNA. The present disclosure provides compositions, systems, and kits comprising a labeled single stranded detector DNA of the present disclosure. The present disclosure further provides methods of detecting a target DNA (double stranded or single stranded) in a sample.