Tramadol HBR-Celecoxib Co-Crystal

The present invention provides a novel 1:1 co-crystal of (rac)-tramadol hydrobromide-celecoxib and processes for the preparation of the same by reacting (rac)-tramadol with hydrobromic acid and celecoxib. It also provides crystalline form of (rac)-tramadol hydrobromide.

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Bibliographische Detailangaben
Hauptverfasser: Golivi, Ramamohana Rao, Jayachandra, Sureshbabu, Jetti, Ramakoteswara Rao
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a novel 1:1 co-crystal of (rac)-tramadol hydrobromide-celecoxib and processes for the preparation of the same by reacting (rac)-tramadol with hydrobromic acid and celecoxib. It also provides crystalline form of (rac)-tramadol hydrobromide.