PRMT5 INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

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Bibliographische Detailangaben
Hauptverfasser: Munchhof, Michael John, Chesworth, Richard, Boriack-Sjodin, Paula Ann, Duncan, Kenneth W, Jin, Lei
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.