INTENSITY MODULATED PROTON THERAPY PLAN OPTIMIZATION FOR LOCALIZED PLAN DEFICIENCIES

A method and system for optimizing an IMPT plan are provided, as well as a computer program product for performing, and an arrangement for planning IMPT. For optimizing the IMPT plan, the following steps are performed. An initial IMPT plan is received, along with anatomical image data of the subject to be treated. Critical proton spots are identified in the initial plan using the anatomical image data. At least one local plan deficiency area associated with the identified critical proton spots is generated. A local treatment plan is then generated for the LPDA by applying robust optimization to it. The optimized treatment plan for delivery to the subject to is then generated by combining the local treatment plan with the initial IMPT plan.