METHOD FOR REMOVING INTERFERING COMPONENTS OF A LIQUID SAMPLE PRIOR TO DISPENSING SAME ON A CHEMICAL REAGENT TEST SLIDE

A method using a chemical analyzer for removing a component of a liquid sample which may interfere with a test performed on a test assay includes the steps of adding the liquid sample to a sample cup, transferring a volume of the liquid sample to a mixing cup containing an IMAC (Immobilized Metal Af...

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Bibliographische Detailangaben
Hauptverfasser: Pelletier, Dominic, Fox, Lucius S, LePage, Wendy O'Malley, Cacavas, Pamela Ann, Lachapelle, Robert W, Steva, Eric Allen, Peck, Evan M, Yerramilli, Murthy V.S.N
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method using a chemical analyzer for removing a component of a liquid sample which may interfere with a test performed on a test assay includes the steps of adding the liquid sample to a sample cup, transferring a volume of the liquid sample to a mixing cup containing an IMAC (Immobilized Metal Affinity Chromatography) resin containing porous beads to form a sample/resin solution in the mixing cup, using a pipette of the chemical analyzer to repeatedly aspirate the sample/resin solution into a disposable pipette tip of the pipette and expelling the sample/resin solution from the pipette tip into the mixing cup to achieve a mixed sample/resin solution in the mixing cup, and allowing the mixed sample/resin solution in the mixing cup to rest undisturbed so that the interfering component of the liquid sample adheres to the porous beads and the beads settle to a bottom portion of the mixing cup, resulting in a refined liquid sample devoid of the interfering component and occupying an upper portion of the mixing cup for later dispensing on the test assay.