PROPHYLACTIC USES OF PARTIALLY OR FULLY REDUCED FORMS OF HMGB1 PRIOR TO INJURY

PROPHYLACTIC USES OF PARTIALLY OR FULLY REDUCED FORMS OF HMGB1 PRIOR TO INJURY

The subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent...

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Bibliographische Detailangaben
Hauptverfasser: Feldmann, Marc, Nanchahal, Jagdeep, Horwood, Nicole, Lee, Geoffrey, Chan, James, Espirito Santo, Ana Isabel
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent the consequence of the anticipated injury.