Therapeutic Nanoparticles Comprising A Therapeutic Agent And Methods of Making And Using Same

The present disclosure generally relates to nanoparticles comprising an endo-lysosomal escape agent, a nucleic acid, and a polymer. Other aspects include methods of making and using such nanoparticles.

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Bibliographische Detailangaben
Hauptverfasser: Boylan, Nicholas Jon, Horhota, Allen Thomas, Song, Young-Ho, Simmons, Matthew John, Joshi, Ujjwal Chaitanya
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure generally relates to nanoparticles comprising an endo-lysosomal escape agent, a nucleic acid, and a polymer. Other aspects include methods of making and using such nanoparticles.