MONOACYLGLYCEROL LIPASE MODULATORS

MONOACYLGLYCEROL LIPASE MODULATORS

3.1.0 and 4.1.0 Azabicycle compounds of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laforteza, Brian Ngo, Garcia-Reynaga, Pablo, Ameriks, Michael K, Berry, Cynthia B, Liang, Jimmy T
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:3.1.0 and 4.1.0 Azabicycle compounds of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, bipolar disorder), cancers and eye conditions.wherein X, Y, R1, R2a, and R2b are defined herein.