METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF

The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.

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Bibliographische Detailangaben
Hauptverfasser:	YIM, Joung Han, KIM, II-Chan, KIM, Tai Kyoung, YOUN, Ui Joung, LEE, Hong Kum, HAN, Se Jong, YEO, Kwon Joo, LEE, Jun Hyuck
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.