UNIVERSAL TAIL PRIMERS WITH MULTIPLE BINDING MOTIFS FOR MULTIPLEXED DETECTION OF SINGLE NUCLEOTIDE POLYMORPHISMS

The present disclosure provides methods and compositions for identifying and discriminating between one or more target nucleic acids within a sample. The disclosed methods may be useful for detecting single nucleotide polymorphisms (SNPs). The disclosed methods may be useful in identifying or detect...

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Bibliographische Detailangaben
Hauptverfasser: MENGE, Karen L, JACKY, Lucien, RAJAGOPAL, Aditya
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides methods and compositions for identifying and discriminating between one or more target nucleic acids within a sample. The disclosed methods may be useful for detecting single nucleotide polymorphisms (SNPs). The disclosed methods may be useful in identifying or detecting the presence or absence of a nucleotide mutation. The use of mutation-specific oligonucleotide probes with universal tails enables specific detection of a SNP target present in a sample.