PROTEASOME ACTIVITY ENHANCING COMPOUNDS

PROTEASOME ACTIVITY ENHANCING COMPOUNDS

The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.

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Bibliographische Detailangaben
Hauptverfasser: Haeberlein, Markus, Foley, Megan, Cullen, Matthew, Tait, Bradley, Hauck, Sheila
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.