GENOME EDITING IN BACTEROIDES

Compositions and methods for genome editing of Bacteroides species are provided herein. RNA-guided nucleobase modification systems are engineered to target specific loci in chromosomal DNA of a target bacteria cell, wherein the genome of the target bacterial cell can be modified.

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Bibliographische Detailangaben
Hauptverfasser: Davis, Gregory D, Eastlund, Erik, Zhang, Zhigang
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions and methods for genome editing of Bacteroides species are provided herein. RNA-guided nucleobase modification systems are engineered to target specific loci in chromosomal DNA of a target bacteria cell, wherein the genome of the target bacterial cell can be modified.