SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Hajare, Anil Kashiram, Palle, Venkata P, Gore, Balasaheb Arjun, Sindkhedkar, Milind Dattatraya, Nair, Prathap Sreedharan, Sethi, Sachin, Kamboj, Rajender Kumar, Lagad, Dipak Raychand, Gudade, Ganesh Bhausaheb, Kulkarni, Chaitanya Prabhakar, Pawar, Chetan Sanjay, Tryambake, Mahadeo Bhaskar, Kulkarni, Sanjeev Anant
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.