ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING
embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeuticall...
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| creator | Baiga, Thomas J Suh, Jae Myoung Liddle, Christopher Downes, Michael Atkins, Annette Fang, Sungsoon Yu, Ruth T Keana, John F.W Evans, Ronald M |
| description | embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject. |
| format | Patent |
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Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210520&DB=EPODOC&CC=US&NR=2021147365A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210520&DB=EPODOC&CC=US&NR=2021147365A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Baiga, Thomas J</creatorcontrib><creatorcontrib>Suh, Jae Myoung</creatorcontrib><creatorcontrib>Liddle, Christopher</creatorcontrib><creatorcontrib>Downes, Michael</creatorcontrib><creatorcontrib>Atkins, Annette</creatorcontrib><creatorcontrib>Fang, Sungsoon</creatorcontrib><creatorcontrib>Yu, Ruth T</creatorcontrib><creatorcontrib>Keana, John F.W</creatorcontrib><creatorcontrib>Evans, Ronald M</creatorcontrib><title>ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING</title><description>embodiments of a method of making the same, and of a composition comprising them are disclosed herein. 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Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>APPARATUS THEREFOR</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB19HP08XcPVvB3U3BzjXAMcvT19HNVcPRzUfB1DfHwdwHL-Dp6e_q5g0VDg4EsHgbWtMSc4lReKM3NoOzmGuLsoZtakB-fWlyQmJyal1oSHxpsZGBkaGhibmxm6mhoTJwqAFGpKBQ</recordid><startdate>20210520</startdate><enddate>20210520</enddate><creator>Baiga, Thomas J</creator><creator>Suh, Jae Myoung</creator><creator>Liddle, Christopher</creator><creator>Downes, Michael</creator><creator>Atkins, Annette</creator><creator>Fang, Sungsoon</creator><creator>Yu, Ruth T</creator><creator>Keana, John F.W</creator><creator>Evans, Ronald M</creator><scope>EVB</scope></search><sort><creationdate>20210520</creationdate><title>ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING</title><author>Baiga, Thomas J ; Suh, Jae Myoung ; Liddle, Christopher ; Downes, Michael ; Atkins, Annette ; Fang, Sungsoon ; Yu, Ruth T ; Keana, John F.W ; Evans, Ronald M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2021147365A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2021</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>APPARATUS THEREFOR</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>Baiga, Thomas J</creatorcontrib><creatorcontrib>Suh, Jae Myoung</creatorcontrib><creatorcontrib>Liddle, Christopher</creatorcontrib><creatorcontrib>Downes, Michael</creatorcontrib><creatorcontrib>Atkins, Annette</creatorcontrib><creatorcontrib>Fang, Sungsoon</creatorcontrib><creatorcontrib>Yu, Ruth T</creatorcontrib><creatorcontrib>Keana, John F.W</creatorcontrib><creatorcontrib>Evans, Ronald M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Baiga, Thomas J</au><au>Suh, Jae Myoung</au><au>Liddle, Christopher</au><au>Downes, Michael</au><au>Atkins, Annette</au><au>Fang, Sungsoon</au><au>Yu, Ruth T</au><au>Keana, John F.W</au><au>Evans, Ronald M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING</title><date>2021-05-20</date><risdate>2021</risdate><abstract>embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and treating or preventing a metabolic disorder in the subject. Additionally disclosed are embodiments of a method of treating or preventing inflammation in an intestinal region of a subject, comprising administering to the subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating FXR receptors in the intestines, and thereby treating or preventing inflammation in the intestinal region of the subject.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING |
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