METHODS AND MICROORGANISMS FOR THE FERMENTATION OF METHANE TO MULTI-CARBON COMPOUNDS

Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of mak...

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Hauptverfasser: ZHAO, Xinhua, WAWRZYN, Grayson Thomas, LI, Xuezhi, SCHMALISCH, Matthias Helmut, HELD, Mark Anton, FARWELL, Christopher Cheyney, CLARK, Louis A, CHAO, Lily Yuin, TRINH, Na My, ORTH, Jeffrey David, DIETZEL, Kevin Lee, KEALEY, James
Format: Patent
Sprache:eng
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Zusammenfassung:Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed.