GENOME ASSEMBLY METHOD, NON-TRANSITORY COMPUTER READABLE MEDIUM, AND GENOME ASSEMBLY DEVICE

Provided is a method of assembling a genome, including: determining the reference appearance rates, that are the appearance rates of all n-base motifs in the nucleotide sequence of a reference genome, in which the n-base motif is a nucleotide sequence containing n bases; and the sample appearance rates, that are the appearance rates of all the n-base motifs in the nucleotide sequences of DNA fragments, calculating the deviations of the sample appearance rates from the reference appearance rates for all the n-base motifs; selecting a predetermined number of n-base motifs having smallest deviations and sample appearance rates of not less than a predetermined value; converting the nucleotide sequences of the DNA fragments into DNA fragments in genome map format using the predetermined number of n-base motifs selected; and assembling the DNA fragments converted in genome map format to generate assemble contigs derived from the DNA in the sample.