POLYMER MATRIX COMPOSITES COMPRISING AT LEAST ONE OF SOLUBLE OR SWELLABLE PARTICLES AND METHODS OF MAKING THE SAME

A polymer matrix composite comprising a porous polymeric network; and a plurality of at least one of polar solvent soluble particles or polar solvent swellable particles distributed within the polymeric network structure; wherein the polymeric network structure is insoluble relative to the soluble p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Waller, Jr., Clinton P, Dehn, Derek J, Nayar, Satinder K
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A polymer matrix composite comprising a porous polymeric network; and a plurality of at least one of polar solvent soluble particles or polar solvent swellable particles distributed within the polymeric network structure; wherein the polymeric network structure is insoluble relative to the soluble particles, wherein the soluble particles are present in a range from 1 to 99 weight percent, based on the total weight of the at least one of soluble particles or swellable particles and the polymer (excluding any solvent); and wherein the polymer matrix composite has particles that at least one of (a) upon exposure to a polar fluid, release at least some component from the polymer matrix composite layer or (b) upon exposure to a polar fluid, absorb some of the polar fluid; and methods for making the same. The polymer matrix composites are useful, for example, in delivery devices comprising the polymer matrix composite, wherein the at least one of soluble particles or swellable particles comprise at least one of an active agent or a released agent.