BCKDK INHIBITORS

BCKDK INHIBITORS

wherein R1, R2, and R3 are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetes, NASH and heart failure.

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Bibliographische Detailangaben
Hauptverfasser: Miller, Russell Alan, Buzon, Leanne Marie, Kormos, Bethany Lyn, Griffith, David Andrew, Filipski, Kevin James, Zhang, Yuan, Bhattacharya, Samit Kumar, Roth Flach, Rachel Jane, Martinez-Alsina, Luis Angel, Reese, Matthew Richard
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:wherein R1, R2, and R3 are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat, for example, diabetes, NASH and heart failure.