SENSOR FOR DETECTING FOOD-BORNE GASTROINTESTINAL IRRITANTS, CONTAMINANTS, ALLERGENS AND PATHOGENS

Embodiments of the present disclosure relate to a sensor that alters its photoluminescent properties upon a binding event between a food-borne analyte and an analyte-specific aptamer (ASA). The ASA may recognize and bind the food-borne analyte, which is referred to herein as the binding event. In so...

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Bibliographische Detailangaben
Hauptverfasser:	TURNER, Raymond Joseph, VIJ, Varun, YADID-PECHT, Orly, VASTAREY, Nikhil Suresh
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	Embodiments of the present disclosure relate to a sensor that alters its photoluminescent properties upon a binding event between a food-borne analyte and an analyte-specific aptamer (ASA). The ASA may recognize and bind the food-borne analyte, which is referred to herein as the binding event. In some embodiments of the present disclosure the ASA is a strand of single-stranded DNA (ssDNA). Some embodiments of the present disclosure the ASA may be conjugated with a chemically modified photoluminescent matrix material. In some embodiments of the present disclosure, the food-borne analyte may be conjugated with a quencher that may be incorporated into the system for reducing false signals.