POTENT AGELASTATIN DERIVATIVES AS MODULATORS FOR CANCER INVASION AND METASTASIS

POTENT AGELASTATIN DERIVATIVES AS MODULATORS FOR CANCER INVASION AND METASTASIS

The present disclosure relates to derivatized agelastatin compounds and methods for the treatment, prevention, or delay of cancer, comprising administering a therapeutically effect amount of the derivatized agelastatin compounds, a pharmaceutically acceptable salt thereof, or a composition thereof t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buchsbaum, Rachel J, Xu, Kun, Movassaghi, Mohammad, Antropow, Alyssa H
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to derivatized agelastatin compounds and methods for the treatment, prevention, or delay of cancer, comprising administering a therapeutically effect amount of the derivatized agelastatin compounds, a pharmaceutically acceptable salt thereof, or a composition thereof to a subject in need thereof. Methods for making the derivatized agelastatin compounds are also provided.