METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING DIABETES

The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylactic glycolic acid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for re...

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Bibliographische Detailangaben
Hauptverfasser:	KARNIELI, Eddy, BECKERMAN, Margarita, LEWIS, Eli Chaim, LEVENBERG, Shulamit, HAREL, Chava
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylactic glycolic acid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.