Pharmaceutical Solid Compositions Containing Ibuprofen Salts

A pharmaceutical, non-effervescent, solid composition comprising a mixture of a pharmaceutically effective amount of a ibuprofen salt and a pharmaceutically acceptable strong base in a molar ratio of from 1:0.01 to 1:0.8, said composition being such that, when dissolved in drinkable water for diluti...

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Bibliographische Detailangaben
Hauptverfasser: Moretto, Alberto, De Lazzari, Alessandra, Dicorato, Lucia
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A pharmaceutical, non-effervescent, solid composition comprising a mixture of a pharmaceutically effective amount of a ibuprofen salt and a pharmaceutically acceptable strong base in a molar ratio of from 1:0.01 to 1:0.8, said composition being such that, when dissolved in drinkable water for dilution, imparts a pH value ranging from 9 to 9.5 to the obtained solution, which do not cause sensory irritation to the oral cavity especially to the back of the mouth and throat, when swallowed.