STABLE AQUEOUS ANTI-TAU ANTIBODY FORMULATIONS

The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidan...

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Hauptverfasser: RINN, Christine, SCHAKER-THEOBALD, Kathrin, RIED, Christian, SIEDLER, Michael, HULSMEYER, Martin, KALETA, Katharina, MEYER, Tanja, ANGSTENBERGER, Jonas, WILBERTZ, Axel, APPENZELLER, Kerstin
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides stable, aqueous, buffered compositions comprising a high concentration of ABBV-8E12, such as a stable, aqueous buffered composition including ABBV-8E12 at a concentration of about 100 mg/ml, at least one buffer, an excipient, a surfactant, and optionally an antioxidant.