BISPECIFIC ANTIBODIES TO TNF-ALPHA AND IL-1BETA AND USES THEREOF

The present disclosure relates to bi-specific antibodies that specifically bind and neutralize both tumor necrosis factor α (TNFα) and interleukin-1β (IL-1β), and to the use of such bispecific antibodies for the therapeutic treatment of TNFα and IL-1β-mediated diseases and disorders.

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Hauptverfasser: NISHIDA, Motohiko, FUNG, Man-Cheong, TAM, Susan H, ZHANG, Di, CHO, Minseon, SHI, Lihua
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creator NISHIDA, Motohiko
FUNG, Man-Cheong
TAM, Susan H
ZHANG, Di
CHO, Minseon
SHI, Lihua
description The present disclosure relates to bi-specific antibodies that specifically bind and neutralize both tumor necrosis factor α (TNFα) and interleukin-1β (IL-1β), and to the use of such bispecific antibodies for the therapeutic treatment of TNFα and IL-1β-mediated diseases and disorders.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BISPECIFIC ANTIBODIES TO TNF-ALPHA AND IL-1BETA AND USES THEREOF
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