BISPECIFIC ANTIBODIES TO TNF-ALPHA AND IL-1BETA AND USES THEREOF

The present disclosure relates to bi-specific antibodies that specifically bind and neutralize both tumor necrosis factor α (TNFα) and interleukin-1β (IL-1β), and to the use of such bispecific antibodies for the therapeutic treatment of TNFα and IL-1β-mediated diseases and disorders.

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Bibliographische Detailangaben
Hauptverfasser: NISHIDA, Motohiko, FUNG, Man-Cheong, TAM, Susan H, ZHANG, Di, CHO, Minseon, SHI, Lihua
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates to bi-specific antibodies that specifically bind and neutralize both tumor necrosis factor α (TNFα) and interleukin-1β (IL-1β), and to the use of such bispecific antibodies for the therapeutic treatment of TNFα and IL-1β-mediated diseases and disorders.