PROCESS FOR PRODUCING HU14.18K322A MONOCLONAL ANTIBODY

PROCESS FOR PRODUCING HU14.18K322A MONOCLONAL ANTIBODY

A fed-batch process for producing Hu14.18K322A monoclonal antibody by culturing a mammalian cell culture in a culture medium including plant protein hydrolysates and a stable glucose concentration is provided, wherein said method yields a population of Hu14.18K322A monoclonal antibodies with increas...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Meagher, Michael M, Reddivari, Muralidhar
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:A fed-batch process for producing Hu14.18K322A monoclonal antibody by culturing a mammalian cell culture in a culture medium including plant protein hydrolysates and a stable glucose concentration is provided, wherein said method yields a population of Hu14.18K322A monoclonal antibodies with increased titer and percentage of afucosylation.