COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS

COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS

and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: METCALF, Andrew Terrance, TARLTON, Eugene, LAIRD, Ellen Ruth, BROWN, Katie Keaton, BARBOUR, Patrick Michael, MORENO, David Austin, PRIGARO, Brett Joseph, PAJK, Spencer Phillip, NEWHOUSE, Bradley Jon, HICKEN, Erik James, REN, Li, COOK, Adam Wade, KAHN, Dean Russell
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:and pharmaceutically acceptable salts, solvates and polymorphs thereof, wherein L, X1, R1, R2, R3, R4, R5 and R6 are as defined herein, for the treatment of BRAF-associated diseases and disorders, including BRAF-associated tumors, including malignant and benign BRAF-associated tumors of the CNS and malignant extracranial BRAF-associated tumors.