FORMULATIONS OF DENGUE VIRUS VACCINE COMPOSITIONS

The present invention relates to formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Jones, Morrisa, Blue, Jeffrey Thomas, Pixley, Heidi Joanne, Green-Trexler, Erin J, Bhambhani, Akhilesh, Ryan, Michael S, Martin, Sherrie-Ann P, Stanbro, Justin, Isopi, Lynne Ann
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.