Multiplexed Lateral Flow Assay Device

A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic elem...

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Bibliographische Detailangaben
Hauptverfasser: Ferreira da Silva, Ademir, Ferreira Ribeiro, Pedro Paulo, Domingos da Silva, Edimilson, Azpiroz, Jaione Tirapu, Mazarakis Rubim, Nara, Steiner, Mathias B, Ferreira, Matheus Esteves, Ohta, Ricardo Luis, Pinto Ferreira, Antonio Gomes
Format: Patent
Sprache:eng
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Zusammenfassung:A multiplexed lateral flow device includes an impermeable internal reservoir having an opening to receive a sample deposition. A fluid distributor pad is arranged in fluid communication with a lower surface of the internal reservoir. The fluid distributor pad includes a paper based microfluidic element having a pattern of a hydrophobic material to distribute a portion of the sample deposition substantially equally among a plurality of flow paths. Lateral flow assays having a plurality of flow lines are aligned with flow paths of the distributor pad. An impermeable top cover has a first window arranged over the opening of the internal reservoir, and at least a second window arranged over the test results of the lateral flow assays. A housing element houses the reservoir, the distributor pad and lateral flow assays. The housing element includes an impermeable bottom cover and a spacer element arranged between the top and bottom covers and, provides a gap between the lateral flow assays and the impermeable top cover.