AUTOMATED SCREENING OF HISTOPATHOLOGY TISSUE SAMPLES VIA CLASSIFIER PERFORMANCE METRICS

Systems and methods are provided for screening a set of histopathology tissue samples representing a region of interest for abnormalities. A pattern recognition classifier is trained on a first set of images, each representing a tissue sample that is substantially free of abnormalities, and a second...

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Bibliographische Detailangaben
Hauptverfasser:	GREGSON, Mark, O'SHEA, Donal
Format:	Patent
Sprache:	eng
Schlagworte:	CALCULATING COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS COMPUTING COUNTING HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA IMAGE DATA PROCESSING OR GENERATION, IN GENERAL INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS PHYSICS
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Beschreibung
Zusammenfassung:	Systems and methods are provided for screening a set of histopathology tissue samples representing a region of interest for abnormalities. A pattern recognition classifier is trained on a first set of images, each representing a tissue sample that is substantially free of abnormalities, and a second set of images, each representing one of the set of histopathology tissue samples representing the region of interest. At least one performance metric from the pattern recognition classifier is generated. A given performance metric represents one of an accuracy of the classifier in discriminating between images representing tissue that is substantially free of abnormalities and images of histopathology tissue samples representing the region of interest and a training rate of the pattern recognition classifier. A likelihood of abnormalities in the region of interest is determined from the at least one performance metric from the pattern recognition classifier.