STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE
An optimized Dipheylthiocarbazone or Dithizone (DTZ) solution was developed with preferred physical and chemical properties to characterize human islets and insulin producing cells differentiated from embryonic stem cells. Application of the newly formulated iDTZ (i stands for islet) over a range of...
Gespeichert in:
Hauptverfasser: | , , , |
---|---|
Format: | Patent |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | QI, Meirigeng VALIENTE, Luis AL-ABDULLAH, Ismail H KHIATAH, Bashar |
description | An optimized Dipheylthiocarbazone or Dithizone (DTZ) solution was developed with preferred physical and chemical properties to characterize human islets and insulin producing cells differentiated from embryonic stem cells. Application of the newly formulated iDTZ (i stands for islet) over a range of temperatures, time intervals and cell and tissue types found to be robust for identifying these cells. The iDTZ, through high transition zinc binding, concentrated in insulin producing cells could also be used to delineate zinc levels in tissue and liquid samples. |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2020319065A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2020319065A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2020319065A13</originalsourceid><addsrcrecordid>eNrjZHANDnF08nFVcPEM8fCM8vdzVQj29wkN8fT3C1Zw9HNRcPMP8g31cUQI-LqGePi7BIMkFEI8XD2DFEKDXXkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBkYGxoaWBmamjoTFxqgBPtS0e</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE</title><source>esp@cenet</source><creator>QI, Meirigeng ; VALIENTE, Luis ; AL-ABDULLAH, Ismail H ; KHIATAH, Bashar</creator><creatorcontrib>QI, Meirigeng ; VALIENTE, Luis ; AL-ABDULLAH, Ismail H ; KHIATAH, Bashar</creatorcontrib><description>An optimized Dipheylthiocarbazone or Dithizone (DTZ) solution was developed with preferred physical and chemical properties to characterize human islets and insulin producing cells differentiated from embryonic stem cells. Application of the newly formulated iDTZ (i stands for islet) over a range of temperatures, time intervals and cell and tissue types found to be robust for identifying these cells. The iDTZ, through high transition zinc binding, concentrated in insulin producing cells could also be used to delineate zinc levels in tissue and liquid samples.</description><language>eng</language><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; PHYSICS ; TESTING</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201008&DB=EPODOC&CC=US&NR=2020319065A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201008&DB=EPODOC&CC=US&NR=2020319065A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>QI, Meirigeng</creatorcontrib><creatorcontrib>VALIENTE, Luis</creatorcontrib><creatorcontrib>AL-ABDULLAH, Ismail H</creatorcontrib><creatorcontrib>KHIATAH, Bashar</creatorcontrib><title>STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE</title><description>An optimized Dipheylthiocarbazone or Dithizone (DTZ) solution was developed with preferred physical and chemical properties to characterize human islets and insulin producing cells differentiated from embryonic stem cells. Application of the newly formulated iDTZ (i stands for islet) over a range of temperatures, time intervals and cell and tissue types found to be robust for identifying these cells. The iDTZ, through high transition zinc binding, concentrated in insulin producing cells could also be used to delineate zinc levels in tissue and liquid samples.</description><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>PHYSICS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHANDnF08nFVcPEM8fCM8vdzVQj29wkN8fT3C1Zw9HNRcPMP8g31cUQI-LqGePi7BIMkFEI8XD2DFEKDXXkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBkYGxoaWBmamjoTFxqgBPtS0e</recordid><startdate>20201008</startdate><enddate>20201008</enddate><creator>QI, Meirigeng</creator><creator>VALIENTE, Luis</creator><creator>AL-ABDULLAH, Ismail H</creator><creator>KHIATAH, Bashar</creator><scope>EVB</scope></search><sort><creationdate>20201008</creationdate><title>STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE</title><author>QI, Meirigeng ; VALIENTE, Luis ; AL-ABDULLAH, Ismail H ; KHIATAH, Bashar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2020319065A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2020</creationdate><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>PHYSICS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>QI, Meirigeng</creatorcontrib><creatorcontrib>VALIENTE, Luis</creatorcontrib><creatorcontrib>AL-ABDULLAH, Ismail H</creatorcontrib><creatorcontrib>KHIATAH, Bashar</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>QI, Meirigeng</au><au>VALIENTE, Luis</au><au>AL-ABDULLAH, Ismail H</au><au>KHIATAH, Bashar</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE</title><date>2020-10-08</date><risdate>2020</risdate><abstract>An optimized Dipheylthiocarbazone or Dithizone (DTZ) solution was developed with preferred physical and chemical properties to characterize human islets and insulin producing cells differentiated from embryonic stem cells. Application of the newly formulated iDTZ (i stands for islet) over a range of temperatures, time intervals and cell and tissue types found to be robust for identifying these cells. The iDTZ, through high transition zinc binding, concentrated in insulin producing cells could also be used to delineate zinc levels in tissue and liquid samples.</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | eng |
recordid | cdi_epo_espacenet_US2020319065A1 |
source | esp@cenet |
subjects | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING |
title | STABLE DITHIZONE SOLUTIONS AND FORMULATIONS AND METHODS FOR THEIR USE |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T00%3A19%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=QI,%20Meirigeng&rft.date=2020-10-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2020319065A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |