CYCLIN-DEPENDENT KINASE 2 BIOMARKERS AND USES THEREOF

CYCLIN-DEPENDENT KINASE 2 BIOMARKERS AND USES THEREOF

Biomarkers are provided that are predictive and/or indicative of a subject's responsiveness to a cyclin-dependent kinase 2 (CDK2) inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of hav...

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Bibliographische Detailangaben
Hauptverfasser: Ye, Min, Favata, Margaret, Yao, Wenqing, Wu, Liangxing, Lo, Yvonne, Sokolsky, Alexander, Chen, Yingnan, Winterton, Sarah
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Biomarkers are provided that are predictive and/or indicative of a subject's responsiveness to a cyclin-dependent kinase 2 (CDK2) inhibitor. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing a disease or disorder associated with CDK2 and for monitoring treatment.