Polymer and dosage form with sustained release properties and resistance against the influence of ethanol

A polymer is polymerized from a monomer mixture containing (a) 70 to 95% by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA) or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 2.5 to 25% by weight of one or more C2 to C6 hydroxy-alkyl esters of acrylic acid...

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Bibliographische Detailangaben
Hauptverfasser:	del Rosario Ferrand, Jessica, Eurich, Thomas, Schattka, Jan Hendrik, Endres, Thomas, Meier, Christian, Hermes, Florian, Jung, Herbert
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	A polymer is polymerized from a monomer mixture containing (a) 70 to 95% by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA) or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 2.5 to 25% by weight of one or more C2 to C6 hydroxy-alkyl esters of acrylic acid or methacrylic acid, (c) 2.5 to 15% by weight of one or more C2 to C8 alkyl esters of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group. The polymer is useful for preparing a dosage form with a sustained release profile and resistance against the influence of ethanol.