METHODS AND INTERMEDIATES FOR THE PREPARATION BILE ACID DERIVATIVES

METHODS AND INTERMEDIATES FOR THE PREPARATION BILE ACID DERIVATIVES

The present invention relates to methods and novel intermediates useful in the preparation of a compound or a pharmaceutically acceptable salt thereof. An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and int...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Whitley, Paul E, lorga, Kayia R, Schaab, Kevin, Chavez, Flavio
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Beschreibung
Zusammenfassung:The present invention relates to methods and novel intermediates useful in the preparation of a compound or a pharmaceutically acceptable salt thereof. An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and intermediates described relates to the synthesis of bile acid derivatives which activate both FXR and TGR5.