ANTIBODIES TO ALPHA-SYNUCLEIN AND USES THEREOF

Disclosed herein are anti-α-synuclein antibodies which preferentially bind to oligomeric α-synuclein over monomeric α-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.

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Bibliographische Detailangaben
Hauptverfasser: DEVIDZE, Nino, AHLIJANIAN, Michael K, HALK, Edward L, GRAEF, John David, MEREDITH, Jr., Jere Ernest
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed herein are anti-α-synuclein antibodies which preferentially bind to oligomeric α-synuclein over monomeric α-synuclein, therapeutic compositions comprising the antibodies, and methods of using the antibodies to treat synucleinopathies.