METHOD AND SYSTEM FOR MULTI-MODAL IMAGING OF TISSUE

There is provided a method for multi-modal imaging of tissue. The method includes: providing a fiber probe over a target area of the tissue, the fiber probe including a plurality of source fiber channels, a plurality of detector fiber channels and a plurality of fiducial marker channels, the plurality of source fiber channels, the plurality of detector fiber channels and the plurality of fiducial marker channels having a predetermined spatial arrangement in the fiber probe; directing light through each of the plurality of source fiber channels of the fiber probe to the target area in succession for performing optical imaging of the target area; obtaining optical imaging data of the target area based on attenuated light from the target area detected through the plurality of detector fiber channels due to said light directed to the target area; obtaining MRI data of the target area based on a MRI of the target area; and coregistering the optical imaging data and the MRI data based on a plurality of fiducial features captured in the MRI data corresponding to the plurality of fiducial marker channels of the fiber probe. There is also provide a corresponding system for multi-modal imaging of tissue.