METHOD FOR THE SAFE INDUCTION OF IMMUNITY AGAINST RSV

Methods of inducing a safe immune response against respiratory syncytial virus (RSV) in a human subject in need thereof, including administering to the subject a composition including recombinant adenovirus including a nucleic acid encoding an RSV Fusion (F) protein including the amino acid sequence...

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Hauptverfasser: GODEAUX, Olivier, SADOFF, Jerald C, WILLIAMS, Kristi Lynn, WIDJOJOATMODJO, Myra Noorely, CALLENDRET, Benoit Christophe Stephan
Format: Patent
Sprache:eng
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Zusammenfassung:Methods of inducing a safe immune response against respiratory syncytial virus (RSV) in a human subject in need thereof, including administering to the subject a composition including recombinant adenovirus including a nucleic acid encoding an RSV Fusion (F) protein including the amino acid sequence of SEQ ID NO: 1, and a pharmaceutically acceptable carrier, in a total dose of from about 1×1010 to about 2×1011 viral particles (vp), are described.