NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF

In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Zlotnick, Gary Warren, Cooper, David, Absalon, Judith, Beeslaar, Johannes Frederik, Phelan, Lynn Marie, Khandke, Lakshmi, Jones, Thomas Richard, Fletcher, Leah Diane, Anderson, Annaliesa Sybil, Farley, John Erwin, Harris, Shannon Lea, Jansen, Kathrin Ute, Kanevsky, Isis, Aste-Amezaga, Jose Miguel, Perez, John Lance, Liberator, Paul
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular polysaccharide. The invention further relates to uses of a composition that includes fHBP, such as, for example, uses to elicit an immune response against N. meningitidis serogroup B strains and non-serogroup B strains. The compositions and methods described herein are directed to administration in humans, including adults, adolescents, toddlers, and infants.