ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR

ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR

Provided are an oral solid preparation composition, including a proton pump inhibitor or a pharmaceutically acceptable salt thereof; and a binding liquid including a basic additive, wherein a content of the basic additive is 2 to 13 parts by weight based on 100 parts by weight of the proton pump inh...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Shin, Kwang Il, Lee, Sang Youb
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided are an oral solid preparation composition, including a proton pump inhibitor or a pharmaceutically acceptable salt thereof; and a binding liquid including a basic additive, wherein a content of the basic additive is 2 to 13 parts by weight based on 100 parts by weight of the proton pump inhibitor or a pharmaceutically acceptable salt thereof; an oral solid preparation including the same; and a method of preparing the same. According to the present disclosure, an oral solid preparation exhibiting a significant reduction in the production of related substances and excellent stability against moisture and low pH is provided.